Linalool
/LIN-uh-lool/
A floral-scented terpene found in cannabis and lavender. Associated with sedating, anxiolytic, and analgesic effects.
In Depth
Linalool is the primary active component of lavender essential oil, which has well-documented anxiolytic effects in clinical trials (Silexan). In cannabis, linalool may contribute to the calming effects of certain strains. Preclinical studies show linalool modulates GABA-A receptors (similar to benzodiazepines), reduces glutamate neurotransmission, and has anti-inflammatory properties. Linalool is also found in over 200 plant species including mint, coriander, and cinnamon.
Related Terms
Further Reading
More in Chemistry
Decarboxylation
The chemical process by which a carboxyl group (COOH) is removed from a molecule, releasing CO₂. Converts inactive cannabinoid acids (THCA, CBDA) into their active forms (THC, CBD).
THCA (Tetrahydrocannabinolic Acid)
The acidic, non-psychoactive precursor to THC found in raw, unheated cannabis. Converted to THC through decarboxylation.
CBDA (Cannabidiolic Acid)
The acidic precursor to CBD found in raw cannabis. Converted to CBD through decarboxylation.
Lipophilicity
The tendency of a molecule to dissolve in fats, oils, and non-polar solvents rather than water. Cannabinoids are highly lipophilic.
Myrcene
The most abundant terpene in most cannabis strains. Produces an earthy, musky aroma. Proposed to enhance cannabinoid absorption and contribute to sedating effects.